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There are a number of abnormalities associated with the use of propranolol during pregnancy, but many of these may be attributable to underlying diseases. I felt extremely jittery, anxious, disoriented, and numbness in the hands and feet on a relatively small dose of Propranolol (20mg three times daily). Significant increases in AUC (27%) and Cmax (58%) and decreases in tmax (23%) of propranolol were noted in this study. photo=inde009t PROPRANOLOL (Inderal(R)) belongs to a group of medicines called beta-blockers. Propranolol should only be given during pregnancy when benefit outweighs risk.
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